Ultilizing the production of vaccine ,the shrimp feeded those with oral method .In orderto assess its effectiveness,it were conducted by deterimining its quantities with challengetechniques .This feeding style through prolonging the feeding time and different living or artificialfeeds for shrimps ,it will be in better results .The oral immunostimulant vaccine will increase the resistance to vibriosis and whitespot syndrome virus (WSSV) of grass shrimps .The survival,growth ,production of grassshrimps and farmer profit will enhance.