Seventy-two Plectropomus leopardus were collected from the wild, from February to April in 2008. Average body weight was 3.10±0.71 kg, body weight range was 1.2-4.7kg, and survival rate was 58.33％. The experiment with HCG and LHRH-A2 injections was conducted on June 11 and we observed the first spawning on June 14 . Spawning period was from June 14 to October 28 and lasted 137 days , including 68 spawning days. The total egg weight was 18,808g（37,616,000 eggs）,including the buoyant eggs（15,471g; 30,942,000 eggs）and the sinking eggs（3,337g; 6,674,000 eggs）. Mean egg weight was 276.59±217.92g（553,000 eggs）,and the highest number of daily spawning was 1,100g（2,200,000 eggs）. During the period. the water temperature was 25.5-30.2℃. Maybe because the seeds in M4（18,424g; 36,848,000 eggs） were selected and mature enough, M4 was the most spawning pond. The larvae were fed with micro-zooplankton which we collected from the sea with lights at night ；on the third day after their hatching ,we added copepoda larvae to the food. The nursing cage was 2.5×2.5×1.2M in size and net mesh was 200. The larvae were alive till the 19th day, and the total body length was 0.78cm. It is necessary to find out the death of the larvae, and we guessed maybe they died from the insufficient food.