CuttlefishSepia pharaonis , with foods a high conversion rate, rapid growth and short life cycle, In order to establish production and releasing technologies become to seawater aquaculture development potential candidate. All 10 cuttlefish total weight of 18.62 kg of 5 male and 5 female fish, was to be stocked at 15 tons indoor cement pond. Female fish spawned from November 23, 2016 to March 9 2017. Total spawning time 8 times, the number of egg s laid range from 170 to 1088 eggs, with a total number of 4,003 of eggs. We carried on white shrimp larvaeLitopenaeus vanname i feeding to 3 stage of age 20, 25 and 30days juveniles and changed to 2 kinds of frozenEuphausia superbaand frozenSpratelloides gracilis as 6 group to juvenile cuttlefish after 42 days rearing. The results were that cuttlefish mean survival rate was to feed age 30days with frozenEuphausia superba51.65±2.33% was the best, following age 30days with frozenSpratelloides gracilis 21.65±11.81%, age 25days with frozenEuphausia superba16.60±0.12%, age 20days with frozenEuphausia superba11.60±7.07%, age 25days with frozenSpratelloides gracilis 8.30±2.40% and age 20days with frozenSpratelloides gracilis 8.30±2.40% was the worst respectively.