Many natural disasters sweep throughout the world in recent years, such as cold snaps, which cased seriously economic losses in aquaculture. React to the demand that government hope to identify the losses whether over 20% realm of the worst hit areas after devastating disruption or not, this plan would offer relatively study of six aquatic organisms to investigate further the reasons why they died for number of days later during the cold weather coming. Meanwhile, we will build the experimental center by mimicking low-temperature condition for realizing their physiology and ecology to be damaged evidence in the future.Besides, through this study could offer some preventive measure and advice for aquatic keepers to decrease the economic losses.