Cuttlefish Sepia pharaonis, with foods a highconversion rate, rapid growth and short life cycle, In order to establishproduction and releasing technologies become to seawater aquaculturedevelopment potential candidate. All 20 cuttlefish total weight of 30.91 kg of 14 male and 6 female fish, wasto be stocked at 15 tons indoor cement pond. Female fish spawned from November28, 2015 to January 12 2016. Total spawning time 31 times, the number of egg s laidrange from 20 to 696 eggs, with a total number of 8,058 of eggs. Then theinitial field trials to 4 group with A group: shrimp Exopalaemon orientis larvae, B group: shrimp Exopalaemon orientis larvae + Artemia salina, Cgroup: initial Artemia salina for 7days + shrimp larvae Exopalaemon orientis for 8- 20days and D group: Artemiasalina as 4 group to juvenile cuttlefish after 20 days rearing. The results werethat cuttlefish mean survival rate was to feed B group 92% was the best, following C group 80%, A group 78.5% and D group 74.5% was the worst respectively. On theother hand cuttlefish mean mantle length of 4 group were all the same and bodyweight to feeding both B group (weight0. 35±0.01g), and C group (weight0. 34±0.01g) jveniles were the best,following D group (weight 0.27±0.05g) and A group (weight0. 26±0.02g) were the worst respectively.