The purpose was to study the bacterial flora and to cleare the bacterial composition inthe digestive tract of shrimps. Here, to investigated the bacterial composition betweennormal shrimp and diseased shrimp in the digestive tract. Our research is to useprobiotic bacteria to add the shrimp culture ponds and shrimp's food to inhibit theVibriosis, WSSV, and Finally to attend the goal of increasing the survival rate of pondshrimps.