Frozen Pacific saury (Cololabis saira) were thawing, ground and hydrolyzed (incubation at 65℃, 2 hr), then separate by centrifuge separator into water-soluble and oil-soluble part. The free amino acid of water-soluble part rich in histidine (348.77 mg/100g) and taurine (120.55 mg/100g). Water-soluble part of Pacific saury were seasoning to produce drink products, and it’s acceptability above the commercial products significantly (P<0.05). The oil-soluble part of Pacific saury contain 9.96±0.04 g/100g EPA and 14.33±0.03 g/100g DHA, were prepared two kind of products, one of is fish oil capsules, and the other is skincare cream, and have good acceptability.