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本實驗之目的在測試外加核苷酸是否可以增強九孔之免疫力。本實驗中，九孔被餵食龍鬚菜及含有四種不同劑量(0%、0.1%、 0.2%及 0.4%)核苷酸混合物的飼料。在餵食實驗的第4及8週，我們採樣進行總血球數、酸性磷酸酶、鹼性磷酸酶及酚氧化酶活性及蛋白質的分析。ㄧ般來說，在第8週時，餵食含有四種核苷酸飼料之九孔的免疫力會比餵食龍鬚菜者高，但僅在酚氧化酶活性方面達顯著差異(P < 0.05)，適當的添加劑量應為0.1%~0.2%。據此，我們推論外加核苷酸可能需要較長的時間(例如8週)才能有效促進九孔免疫力的增強。

The aim of the study was to investigate whether exogenous nucleotide increases the immune activity in small abalone. In this experiment, we fed the abalone with fresh Gracilaria tenuistipitata and 4 artificial feeds containing different contents of nucleotides, i.e., 0%, 0.1%, 0.2%, and 0.4%. After 4 and 8 weeks, the abalone were bled and total hemocyte number, enzyme activities of acid phosphatase (ACP), alkaline phosphatase (ALP) and phenoloxidae (PO), as well as protein concentration in hemolymph were analyzed. The result showed that generally the immunity in the abalone fed with feeds containing exogenous nucleotide mixture were higher than the ones fed with Gracilaria at 8 weeks. But only PO activity between the ones fed with Gracilaria and 4 feeds significantly differed (P < 0.05). The suitable adding concentrations should be 0.1%~0.2%. We supposed that exogenous nucleotide could need more time (e.g., 8 weeks) to produce an enhancing effect on immunity of the shellfish.