Difference Poultry meal sources for apparent digestibility determinations of Cobia. The best is Vensta poultry meal (Import from Canada) that APD(apparent protein digestibility) and ALD(apparent lipid digestibility) is 84.1% and 85.1%. Using this local poultry meal replace fish meal various levels of 0、20、40、60、80%,to make experiment diets protein contend 45% and lipid contend 10%. Replacement lower 40% are not significantly different on growth for Fed 14 weeks. The optimal dietary level is 19.5% of poultry meal replacement fish meal by broken –line regression analysis on percent weight gain. Determination the cobia muscle, the proximate composition (g/100g) not significantly different of the cobia fed experiment diets for 14 weeks.