The grouper is fish species with high economic value, and there are about 400 species all over the world. The grouper aquiculture had been well-developed in Taiwan, but the most severe impact in grouper rasing course is significant mortality resulted from NNV and Iridovirus and leaded to grouper in low survival state.Statistical data about other
pathogens such as bacterail, mycotic and parastitic pathogens affected grouper was rare, so it is hardly to set epidemiological data bank. Our research will set a grouper cases collective station in Pintung, and develope the epidimiological data bank through collecting diseased samples constantly. We will develope a rapid diagnostic technique for grouper infectious diseases to service fishermen.