The research plan sep up the aquatic animal disease diagnostic station, and sep up the data bank of prevalance from diseased grouper through collecting cases persistently to refer to epidemiological research in Gia Dong Town, Pintung County, and develope rapid dianostic technique for important grouper diseases and provide more convinient to fisherman. We have collected 965 diseased grouper cases from January to October, we sum up the data base on several items including poor water quality, parastic, bacterial, viral and others, and the prevalance from higher to lower are poor water quality/453, parastic/439, bacterial/349, others/123 and viral/58. The The poor water quality was abnormal value on 4 tested items and the nitrous acid, ammonium, pH and organic matter are all included. The prevalence of parasitic diseases are Cryptocaryonosis/230, Datylogyriasis/177, Trichodinosis/82, Sea lice/82, Leeches/40,
Ambiphrya/11, Amyloodiniosis/8, Heterophyiasis/6. The bacterial disease are divided into bacterial dermatitis/349 and interal infection (peritonitis)/41. The viral disese cases are 58 totally, are Iridovirus and NNV. The research find, the prevalence of bacterial disease are more than last year, and the Mycobacterium infection can be diagnosed in our research, this kinds of infection may be resulted from fishing net.