Catch amount of sharptail mola, Masturus lanceolatus , is the highest in the total catch of Molidae (80-90%), it is economically valuable. Sharptail mola was categorized to least concern by the International Union for Conservation of Nature (IUCN) in 2015. However, the reproductive biology and feeding ecology of sharptail mola are still rare. The aims of this study are to exploring the reproductive biology and foraging of sharptail mola in east of Taiwan from January 2003 to September 2018. The length measurement and samples of gonads, stomach content and muscle were collected from Nanfangao, Shinkang, and Hualien fish markets. Results indicated that the gonadosomatic index of female sharptail mola reached the highest and the hydrated oocytes and postovulatory follicles were found in April. Male sharptail mola with developing testis was discovered from April to August. The gonads of sharptail mola, body length <100 cm, were immature. It is estimated that the gonads of sharptail mola tend to mature after it grows 100 cm and the spawning season might be April to August. Sharptail mola tends to feed on jellyfish and salps in east of Taiwan, and their δ 15 N values increase with the body length.