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裸胸鯙酵素水解物之抗氧化活性評估

  • 日期:103-09-30
  • 計畫編號:103農科-11.3.2-水-A2(4)
  • 年度:2013
  • 領域:漁業科技研發領域
  • 主持人:林慧秋
  • 研究人員:高雪卿、薛月娥、廖紫嬿

植物和動物的蛋白質為所熟知的生物活性胜肽的來源。胜肽具有多種生物活性,包
括:消炎,抗氧化活性,降低膽固醇和降血壓(ACE抑制能力)效果。血管收縮素轉
換酶(ACE)有心血管功能的關鍵作用。食物中的蛋白質胜肽與合成藥物相比是較溫
和、安全和容易吸收。因此,從食物中的蛋白質酵素水解釋放的胜肽具有不同的生
物活性已能被普遍接受。此外,胜肽和蛋白質在食品中作為抗氧化劑的使用的需求
也日益增加,由於成本低,安全性和其固有的營養和功能值。另一方面,水解蛋白
預防高血壓功能性食品與血管收縮素轉換酶抑制活性的發展大有潛力。隨著國人對
本身健康意識的重視,愈來愈多人關心如何減少罹患相關疾病的機率,其中又以抗
氧化與降血壓之題目最受到注意。因此,近年來食品中所含之生理活性物質逐漸受
到重視。裸胸鯙俗稱為薯鰻或錢鰻,為珊瑚礁區重要的肉食性魚類,也是近海經濟
性食用魚種。本研究擬探討裸胸鯙經過不同酵素水解作用後之的抗氧化活性,後續
將會再進行抑制血管收縮素轉換酶功效,希望提供做為保健新素材之參考。

研究報告摘要(英)


Plant and animal proteins have been well known as sources of bioactive
peptides. Peptides might exhibit various bioactivities, including antiinflammatory,
antioxidant activities, cholesterol-lowering ability, and
blood pressure-lowering (ACE inhibitory) effects. Angiotensin-converting
enzyme (ACE) has a critical role in cardiovascular disease. The peptides
derived from food proteins are considered to be milder, safer, and easily
absorbed compared with synthetic drugs. Thus, enzyme hydrolysis peptides
from food proteins may exhibit different biological activities has been
generally accepted. Besides, peptides and proteins as antioxidants in
food are increasing due to the low costs, safety, and their inherent
nutritional and functional values. On the other hand, protein
hydrolysates with angiotensin converting enzyme inhibitory activity have shown great promise in the development of a novel therapeutics and for
functional food for preventing hypertension. With the awareness of people
on their health, more people are concerned about how to reduce the
incidence of disease, especially in antioxidation effect and decreased
blood pressure problems. Therefore, in recent years, the food contained
in the physiological active substances gradually is taken important.
Moray eels are the commercially important fish species in Taiwan. This
study was to investigate of moray eel using different enzymatic
hydrolysis the antioxidant activity and inhibition of angiotensinconverting
enzyme effect, hope new material provided as a reference for
health food.