農業部水產試驗所全球資訊網

本計畫將研發如何將海木耳養殖與傳統的養魚系統作結合，改善養殖生物(包括石斑 及觀賞魚等)的養殖成果，並生產海木耳，提供給子計畫進行自海木耳分離並測試具 生物活性之成份，以發展為具功效性之高價位產品，進而提升養殖產品價值，有利 新的養殖海藻產業的開創。相較廣被熟知、使用的大型紅藻石花菜與龍鬚菜，海木 耳具可養殖、可食用、未知生物活性等利基。目前尚無海木耳之生物活性的研究或 專利，有利於搶先研究及專利佈局。本計畫鎖定抗發炎、心血管保護、促傷口復原 、藥妝等用途，以離體系統篩選其酒精或水粗萃物的生物活性，並在斑馬魚或大白 鼠模式上驗證及評估其安全性。同時，分析其活性成份，以其最大量物質作為活性 指標成份，建立其標準生產程序。

研究報告摘要(英) To promote the new aquaculture industry of edible macroalgae Sarcodia suieae, we will develop the integrated aquaculture of fish and red macroalgae, and assay the bioactivities of the harvest algae, to enhance the add-value of both products. We aim to find how to integrate the tank algal and fish culture to improve the fish (edible and ornamental) production, and harvest the macroalgae S. suieae for its bioactivity assay. Compared with the widely-used red macroalgae, Gelidium and Gracilaria, and well-known bioactivities, there are three advantages of S. suieae: cultivatable, edible, and unknown bioactivities. There are no previous studies or patents that explore the possible bioactivities of S. suieae. Therefore, we will conduct bioactivity evaluations of ingredients extracted from S. suieae. Firstly, we will use in vitro model to screen e t h a n o l o r w a t e r e x t r a c t s o f S . s u i e a e b y a n t i - i n f l a m m a t o r y , cardiovascular protection, wound healing, and cosmetic assay. Secondly, we will examine the possible in vitro bioactive effects of these potential extracts of S. suieae by using in vivo zebrafish or rat models. Further, we will examine the possible effects of ingredients extracted from S. suieae on a rat model for safety evaluation. We will then analyze the composition of the bioactive extracts of S. suieae in order to use one maximum ingredient as an indicator. Collectively, we will establish the standard production protocol of bioactive ingredients extracted from S. suieae.