The main objectives of the project is to implement the function of genetically modified aquatic organism facility, including (1) operational management of "Genetically Modified Aquatic Organism Facility"; (2) execution of gene flow model studies of genetically modified ornamental fish, and assessment the possibility of fluorescent gene transfer to microorganisms; and (3)research the application of the new biotechnology (gene editing) of aquatic products, enrich the safety risk assessment information for genetically modified aquatic organisms, technical platform modification and functional enhancement. The purpose is to provide a well-isolated and standard-qualified experimental structure, and establishing an access to assess the risk about aquatic GMOs, in order to effectively control and mitigate the impact on the environment and ecology, and to enhance the development of aquatic biotechnology industry in Taiwan.